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First, the law raises costly barriers to entry for new participants in the tobacco sector, many of which would not have been constrained by the terms that applied to the major manufacturers voluntarily as part of the Master Settlement Agreement, nor without the law, the significant fees now imposed on the tobacco industry to fund FDA oversight

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[34] When e-liquids are heated, by-products such as formaldehyde, acetaldehyde, and acrolein can form, at levels that depend on operating conditions and liquid composition

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World J Pharm Res 2015;10:2304-11