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In brief, the major mechanisms of smoking-induced CV disease (many of which are overlapping) are 1) oxidative injury, 2) endothelial damage and dysfunction, 3) enhanced thrombosis, 4) chronic inflammation, 5) hemodynamic stress, 6) adverse effects on blood lipids, 7) insulin resistance and diabetes, 8) reduced oxygen delivery by red blood cells, and 9) arrhythmogenesis

Effect of cigarette smoke components on vascular smooth muscle cell migration toward platelet-derived growth factor BB

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