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[DOI] [PMC free article] [PubMed] [Google Scholar] Hodgson E.Introduction to Biotransformation (Metabolism)

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However, the heterogeneity of the tumors with APOBEC signature in this cohort made it difficult to interpret any associations regarding APOBEC signature co-occurring with EGFR mutation and within specific ethnicities [22]

Tar content appears to exhibit a predominantly polygenic genetic architecture To further investigate the genetic basis of tar content in tobacco, we conducted a genome-wide association study (GWAS) using phenotypic data from 436 tobacco accessions