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Science and data Cumulative health effects When projects or actions are proposed that might affect pollution levels in an area, communities want to know how it will affect human health when combined with other pollutants and stressors in their community

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No clear-cut genotype-phenotype correlations have emerged so far, except that COL5A2 variants seem to result in a more severe phenotype, although numbers are still limited
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In reality, its a smoky haze that has settled over the trees and buildings, leaving an acrid taste in peoples mouths and irritating their eyes

Alternatively, PZA can be initially oxidized to 5-hydroxy-pyrazinamide (5-OH-PZA) by XO, followed by amidase-mediated hydrolysis to 5-OH-PA