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Decisive evidence that increased adipose tissue lipolysis contributes to nicotine plus HFD-induced hepatic steatosis derives from studies showing that acipimox, an inhibitor of adipose tissue lipolysis, treatment significantly prevented nicotine plus HFD-induced increase in hepatic TG levels and hepatic steatosis (Figure 2) (42)

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10.1016/j.jgg.2021.11.005 [DOI] [PubMed] [Google Scholar] 134.Alqrad MAI, El-Agamy DS, Ibrahim SRM, Sirwi A, Abdallah HM, Abdel-Sattar E, et al

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