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While our category volume share of Modern Oral in key markets was 28.0%, down 240 bps, this was mainly driven by the reduction in volume share in the large U.S

Conclusion After the exclusion of other factors affecting uric acid levels, the significant low plasma uric acid level in smokers was attributed to a reduction of endogenous production as a result of the chronic exposure to cigarette smoke that is a significant source of oxidative stress

Duhalde-Vega, M

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Health care use by frequent marijuana smokers who do not smoke tobacco