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1.7 Parthanatos as target in cancer treatment Parthanatos is a cell death mechanism controlled by PARP-1 and is distinct from apoptosis and necroptosis (Harraz et al., 2008) (Figures 1, 2)

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Furthermore, autophagic flux restoration induced by metformin can be also related to sirtuin type 1 activation [125]

-hydroxybutyrate enhances bovine neutrophil adhesion by inhibiting autophagy

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