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[119] Benzoic acid is the most used acid to create a nicotine salt

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Treatment of endothelial cells by nicotine induces calcium internalization and accumulation via 7nAChR activation and induction of angiogenesis [287]

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The specific objectives include determining the levels of heavy metals in the tobacco of traditional cigarettes, identifying the main factors responsible for variations in heavy metal content across different cigarette brands, examining the correlations between various toxic metals, and evaluating the health risks linked to human exposure to these harmful elements