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Besides being involved in synthesis, they ensure tubular reabsorption, which exceeds 90% of the filtered load [19]

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For example, the reaction of carbonyl compounds with a Grignard or organolithium reagent is 1,2-addition: Both the Grignard and especially organolithiums are very strong bases, and stronger bases tend to give 1,2 carbonyl addition reactions while weaker bases give 1,4 conjugate addition

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Its name is derived from Body Protection Compound , reflecting its relationship to peptide sequences identified in gastric protein research