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Guo, The value of short- and long-acting glucagon-like peptide-1 agonists in the management of type 2 diabetes mellitus: experience with exenatide

Constipation may develop as gastric emptying slows more noticeably

While treatment is only applied upon clinical disease manifestation, autoimmune diseases develop over years - starting from the loss of tolerance towards self (autoimmunity), which, upon so far unknown trigger factors, may progress to clinically overt autoimmune disease

Essentially, its an electrochemical gradient across the inner mitochondrial membrane

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New Indications Extend the Story Science continues to push GLP-1s beyond weight loss