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cigarette smoke induces cytoplasmic p53 accumulation Chronic Smoke-Induced Epigenomic Changes Precede Sensitization of Bronchial Epithelial Cells to Single-Step Transformation by KRAS Mutations Dysregulation of immunity by cigarette
Description
The p53 target p21 competes with Keap1 for Nrf2 binding, resulting ultimately in a stable and activated Nrf2 that upregulates the expression of several genes through binding to AREs [54]

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METHODS We followed the methods of He et al

MDM2 binds and inhibits vitamin D receptor

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doi: 10.1016/j.freeradbiomed.2021.06.013
