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This resembled the rate of increase in CR levels with each population doubling (Figure 2, B and C), indicating that creatinine ribosylation, and not creatinine availability, was the rate-limiting step for the conversion of creatinine to CR

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[] Calculated from data provided by Scott Daragh, State of Michigan Office of Revenue and Tax Analysis, in an interview conducted by James Hohman, Mackinac Center for Public Policy, September 26, 2008