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Description
Unfolded protein response (UPR) is a cellular defense mechanism to reduce protein-folding stress in the endoplasmic reticulum (ER)
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The long-lasting and frequent presence of paan and gutkha in the mouth around the gums leads to inflammation of the oral mucosa, which causes the activation of T-cells and macrophages, and ultimately the release of prostaglandins (PGs)
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In 1652, "an unfortunate fire" caused "great losses" for the family, and Johnson applied to the courts for tax relief
