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As a defense mechanism, macrophages can inhibit HIV replication in its cytoplasm by activating p53/p21/CDK1 pathway-mediated cell-cycle arrest 107

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Tobacco smoke condensate induced the relative mRNA expression of SASP factors (Fig

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J., Lerner, N

As DNA methylation is mainly catalyzed by DNA methyltransferases (DNMTs), researchers found that DNMT1 expression was significantly higher in the lung tissues of the smokers compared to the expression in the nonsmokers [27]
