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Posttranscriptional silencing of the lncRNA MALAT1 by miR-217 inhibits the epithelialmesenchymal transition via enhancer of zeste homolog 2 in the malignant transformation of HBE cells induced by cigarette smoke extract

2022;11:e025266

Upon UVR-induced DNA damage, different pathways lead to the dissociation of the p53/mouse double minute 2 (MDM2) inhibitory complex [28] and two major kinases, ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR), mediate p53 phosphorylation, preventing its degradation [29]

U6 snRNA was used as an internal control for relative quantification of miRNA expression levels