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If your lip darkening matches the pattern described in this article (diffuse, concentrated on lower lip and vermilion border, developed gradually over years of smoking), it is almost certainly smoker's melanosis rather than something more serious

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Some parents wonder whether their child needs antibiotics

Yona D, Sari SHJ, Sudono CVA, Siburian ASJ, Wahyudi AD (2024) Alarming cigarette butts contamination on sandy beaches of East Java, Indonesia

Traffic exposure and incident venous thromboembolism in the atherosclerosis risk in communities (ARIC) study