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Peripheral artery disease is characterized by a buildup of cholesterol in the arteries that carry blood to the legs, resulting in reduced blood flow, pain in the limbs, diminished wound-healing abilities in the legs and several other symptoms that can become serious

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The use of aluminum alloy also brings environmental-friendly benefits

Tob Control 2017;26:e97-105

They typically use replaceable batteries (usually 9-volt or AA) or lithium batteries that are sealed inside and last 10 years