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in Mayo Clin Womens Healthsource , Vol

Notably, some studies have shown that the acute increase in systolic blood pressure, diastolic blood pressure , and heart rate dilutes over time, which means that a person may adapt over time and not experience increased blood pressure to the same degree as initially

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This consistent body of evidence, from observational studies in humans to controlled animal research, solidifies the understanding that nicotine is not just a minor factor but a significant contributor to hair loss