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doi: 10.1016/j.biomaterials.2020.120128

Neuroplastic changes induced by physical exercise have been thought to mainly involve the striatum and prefrontal cortex, as well as modulation in the release of DA, cytokines, and neurotrophic factors (such as the brain-derived neurotrophic factor), increased corticomotor excitability, improved connectivity in sensorimotor networks, and changes in DA receptor activity ( Hence, both exercise, especially moderate anaerobic physical exercise, and a healthy diet rich in plant-derived nutrients, can positively affect PD incidence and progression, by stimulating neurotrophic factors, altering the diversity of the gut microbiome, improving barrier permeability, and increasing the levels of SCFAs- producing bacteria (Raber and Sharpton, 2023)

Adapted from Shankar V

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For instance, Type IV is suitable for dark skin and Type V is for very dark skin

The effect of an adapted digital mental health intervention for sickle cell disease on engagement: a pilot randomized controlled trial