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To make an APPH case against flavored products, the FDA must show that flavors cause vaping uptake AND that the behavioral response to making flavors unavailable legally would not lead to a more harmful pattern of tobacco and nicotine use, for example, smoking or use of unregulated, criminally supplied ENDS
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Availability was determined by three separate proxy measures (number of users as determined by household surveys, number of seizures by law enforcement agencies and estimates of the market size)
Cravings are both mental and physical, Dr
