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That began to ease, and with the legalization of cannabis for recreational use in many states, more researchers are now exploring the consequences of the habitual use of weed

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it compromises the responses of the bronchial epithelium by modifying the expression and activation of innate immunity receptors and determines the destruction of desmosomes and tight junctions with increased permeability to allergens, pollutants, and infectious agents and the release of inflammatory mediators (IL-8, IL-1, sICAM-1) 15