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Silencing of miR122 has been shown to upregulate CAT-1 ( SLC7A1 ) expression, and subsequently increase arginine uptake to maintain large intracellular arginine pools for nitric oxide (NO) synthesis, resulting in increased resistance to the multi-kinase inhibitor sorafenib (Kishikawa et al., 2015)

At physiological levels, they function as crucial signaling entities that regulate cell growth, differentiation, and survival [3]

GLUTATHIONE, a naturally occurring protein, is called a peptide
Access this article Similar content being viewed by others References Alfafara CG, Kanda A, Shioi T, Shimizu H, Shioya S, Suga K (1992a) Effect of amino acids on glutathione production by Saccharomyces cerevisiae

The Spanish Ministry of Economy and Competitiveness supported EF-S and VG (BFU201678265-P), PA (BFU201679313-P and MDM-20160687), and AM-V (BFU201564408-P)
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