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While the MTT data cannot be translated directly to in vivo human effects, they do raise concern about the potential for these chemicals to cause harm to users at the concentrations currently used in some refill fluids

Adv Chronic Kidney Dis 20(2):165174 Sales CH, de Pedrosa L, FC, (2006) Magnesium and diabetes mellitus: their relation

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Role of maternal smoking and maternal reproductive history in the etiology of hypospadias in the offspring

In both submerged cultured systems and airliquid interface (ALI) exposure models, 6-MN produces higher levels of reactive oxygen species (ROS) and enhanced cytotoxicity relative to nicotine, posing great risks to pulmonary diseases