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Sequencing based on the 16S amplicon, for example, could detect the variation in GM diversity between populations

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General mechanisms of nicotine-induced fibrogenesis

One primary endogenous source of ROS is the enzyme NADPH oxidase (NOX), which catalyzes the transfer of electrons from cytoplasmic NADPH to molecular oxygen, resulting in the formation of superoxide anions that react with NO to form peroxynitrite, a highly unstable species that can generate further ROS [21,22]

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