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After the introduction of rescue inhalers in the 1950s, use of asthma cigarettes fell off

The most commonly reported unwanted effects with nicotine e-cigarettes were throat or mouth irritation, headache, cough, and feeling sick

Alcohol is highly addictive and some people can have a genetic predisposition to alcoholism

36 (p12) Tobacco Industry Resistance in the 1980s and 1990s In the 1980s, the American Medical Association (AMA) and US Department of Health and Human Services viewed tobacco promotions targeting youths and the resulting youth tobacco use as an increasingly serious public health problem

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