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They have a mood-altering effect on the brain, increasing dopamine in the striatum at a similar magnitude as nicotine, by 150% to 200%

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The need for increasing amounts of nicotine or more frequent nicotine use to achieve the same results drives addiction and physical dependency

If marijuana was used in a state where it is legal, then departments need to consider that as well

Subclinical neuropathy, defined by the presence of abnormal nerve conduction, but no clinical complaints or symptoms, has been described in chronically exposed individuals [Tseng 2003
