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These medications also slow gastric emptying, which could potentially affect bowel function, though no direct link to diverticulitis flare-ups has been established

For those considered overweight or having obesity, losing 5% or more of initial weight is linked to lessening cardiometabolic disease risk, with reductions in blood pressure, LDL cholesterol, triglycerides, and glycemia
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6,9 Individuals with T2D should be categorised into different CV risk groups ( Table 1 )

The similar risk reductions observed in clinically defined ALD, laboratory-defined ALD (HR 0.36), and ALD requiring medications (HR 0.32) suggest that semaglutides benefits extend beyond subjective clinical assessments to include objective laboratory parameters and treatment needs

The cohorts differed in demographics, comorbidities, and medications