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[2] The long-term health outcomes for individuals who experience GTS are not known

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Cognitive Effects Nicotine has been shown in multiple human and animal studies to improve several facets of cognition, including attention, working memory, fine motor function, and episodic memory

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In general, stimulation of this system has an anti-inflammatory effect.(13) In animal models of systemic inflammatory disease, such as sepsis, acute lung injury and viral myocarditis systemic administration of nicotine suppresses inflammation and has a beneficial effect on mortality