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ADSCs are easily isolated from adipose tissue discarded during liposuction or other surgeries, and these ADSCs can be cultured in vitro and generate large numbers of ADSC-EVs

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Ann N Y Acad Sci 939:162178 [DOI] [PubMed] [Google Scholar] 147.Vogelzangs N, Beekman AT, van Reedt Dortland AK, Schoevers RA, Giltay EJ, de Jonge P, Penninx BW (2014) Inflammatory and metabolic dysregulation and the 2-year course of depressive disorders in antidepressant users

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doi: 10.1016/j.fct.2017.04.002

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It was then hypothesized that chemotherapy causes barrier dysfunction, resulting in increased systemic exposure to bacterial products and metabolites, which in turn promotes systemic inflammation and pain

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