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PSM validation We validated the PSM prediction accuracy between the development sample (2017 inspection data) and two separate validation samples (2018 or 2019 inspection data) based on the following steps: (1) we calculated the predicted PSM score at each inspection in 2017, 2018 or 2019 based on previous 2-year inspection results at the zip code level (20152016, 20162017 or 20172018) and other multilevel contextual factors as predictors (see equation 2)

While inhalation of acrolein promotes airway hypersensitivity responses, it may stimuli neutrophil accumulation in the airway, thereby contributing to immune tolerance [109]

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