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Description
In an ( ex vivo ) hypertrophy model, hearts from ANG-II-treated mice exhibited decreased insulin sensitivity with markedly reduced glucose oxidation rates (Mori et al., 2013), whereas clinical trials in healthy subjects using the hyperinsulinemic euglycemic clamp technique showed that acute and chronic hyperinsulinemia increases RAAS activation (Rooney et al., 1991
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22 March 2016
Two groups were compared by using two-tailed Mann-Whitney U test or two-tailed unpaired t -test
and J.W.L
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