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Interestingly, it is found that GSTP1 expression is regulated by the Keap1-Nrf2-ARE pathway and GSTP1 catalyzes the S-glutathionylation of cysteine residues of Keap1 protein, while S-glutathionylation of Keap1 leads to Nrf2 activation and increases the expression of GSTP1 (Ikeda et al., 2002

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