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For example, scientists gave nicotine (by injections) to adolescent rats and found the same increased number of nicotinic receptors in rat brains as seen in human brains

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Flavor bans, effective taxation, comprehensive advertising restrictions and the inclusion of vaping and heated tobacco in all smoke-free laws are no longer optional these are essential measures to prevent cardiovascular disease. He concluded with this: Science is clear: the cardiovascular toxicity of nicotine is evidence-based by now