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(e) Reactive oxygen species Cellular metabolism of BN or BQ components may also generate reactive oxygen species (ROS), such as superoxide anion radicals (O 2 . ) and hydrogen peroxide (H 2 O 2 ) at pH greater than 9.5 [15]

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In a pioneering study, Glantz and Smith 39 examined the consequences of smokefree restaurant ordinances in municipalities in California and Colorado over the period 1985-1992