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While they advise against it for young people or non-smokers, they do recommend it as a quitting tool for smokers for the health benefits of switching

2016) and youth and young adults (Primack et al

A statistical framework for SNP calling, mutation discovery, association mapping and population genetical parameter estimation from sequencing data
These findings further elucidate the metabolites of tobacco leaves were significantly impacted by the application of BSP1
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