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Toxicology Reports, 7, 602-609

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Starting with a low dose, typically 3 mg, allows the body to adjust to the medication, reducing the likelihood of gastrointestinal side effects

Lower scores are better , thus the authors considered this data as potential evidence supporting slowing of disease progression

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Time to 10% Loss: Participants reach 10% weight reduction in 24 weeks, compared with 36 weeks for comparators
