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95% CI 0.580.75)

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The reason is that drugs deliver synthetic appetite-suppressing chemical messengers like GLP-1, GIP, and glucagon agonists at levels astronomically higher than normally produced by the body

Future studies should investigate this crosstalk in the context of GLP1R agonism and the suppression of Notch-mediated therapy resistance

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1 Introduction Metformin is a synthetic derivative of guanidine derived from the guanidine alkaloid of the plant named Galega officinalis L