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Most probiotics contain somewhere between 1 and 10 billion CFUs per serving, though its not uncommon for multi-strain probiotics to contain even more

Whilst one study on L cell-like lines did not support a direct effect of metformin on L cells to mediate this effect [60], a more recent study has reported a direct effect of metformin on these cells, where an increase in the expression of the gene encoding proglucagon by metformin is mediated via a -cateninTCF7L2-mediated mechanism [63, 65]

As of May 2026, FDA has also proposed excluding compounded semaglutide, tirzepatide, and liraglutide from the 503B Bulks List, with a public comment period closing June 29, 2026

So, technically it does not qualify as a diet

Ozempic EPAR public assessment report (full PDF)

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