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Chronic Suppression of Glucagon-Like Peptide-1 Receptor (GLP1R) mRNA Translation in the Rat Bed Nucleus of the Stria Terminalis Reduces Anxiety-Like Behavior and Stress-Induced Hypophagia, But Prolongs Stress-Induced Elevation of Plasma Corticosterone

2 , 2021 FDA

This distinction is essential in any clinical or research discussion

This hidden consequence carries serious implicationsnot just for physical performance, but also for long-term health, bone density, metabolic function, and even joint stability

Evaluating the long-term outcomes of GLP-1RA therapy on ICP and vision could solidify their role in IIH management, potentially establishing them as first-line or adjunctive therapies in selected patients

Adverse events in clinical trials must be reported to the trial team and sponsor