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doi: 10.1007/s11011-024-01347-2
Why GLP-1 Injection Site Reactions Happen GLP-1 medications are given into the subcutaneous fat layer, which means the skin and surrounding tissue interact directly with the medication

Diabetes Metab Syndr Obes 2016;9:201205 [DOI] [PMC free article] [PubMed] [Google Scholar] 54.Nguyen H, Dufour R, Caldwell-Tarr A

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