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Additionally, certain outcomes, such as reductions in DHEAS and total testosterone levels, were not consistently significant when compared to metformin, highlighting potential variations in responses based on the comparator group

EXamination of cArdiovascular outcoMes with alogliptIN versus standard of carE in patients with type 2 diabetes mellitus and acute coronary syndrome (EXAMINE) Am Heart J

Such convenience has also improved physician preference and patient acceptability, and net effect has increased prescription rates

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In patients with gout or hyperuricemia, a pre-treatment baseline helps distinguish medication effects from pre-existing conditions