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34 The trial had a total of 731 patients with a baseline mean A1C of 8.2% and a baseline total daily dose of insulin ranging from 56 to 62 units, depending on the treatment group

113 Patients with active UC and CD had higher amounts of bioactive GLP-2 than healthy controls, according to a study by Xiao et al

Pharmacokinetic studies have shown reduced exposure to ethinyl estradiol and progestins after tirzepatide initiation, with the greatest effect occurring after initial doses and dose escalations

However, current and next-gen obesity therapeutics have the potential to vastly improve health outcomes

A patient starting at 250 pounds may lose 50-55 pounds (22%), while someone beginning at 180 pounds might lose 25-30 pounds (15-17%) on the same doseboth represent equivalent percentage weight loss but different absolute numbers

By supporting healthy glucose levels, this approach not only stabilizes energy levels throughout the day but also plays a significant role in preventing the sharp insulin spikes that can lead to fatigue and irritability