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Fludra M, Kobosko J, Gos E, Paluchowska J, Skarzynski H

The standard protocol involves weekly dose increases from 0.25 mg up to 1.0 mg or 2.4 mg, but some individuals tolerate this progression poorly because genetic variants in the GLP1R gene affect how efficiently their cells respond to the drug

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It is marketed under well-known brand names such as Wegovy, which is approved for weight management, and Ozempic, approved for treating type 2 diabetes

Perdomo CM, Cohen RV, Sumithran P, Clment K, Frhbeck G