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Abstract Glucagon-like peptide-1 receptor agonists are a class of drugs that mimic a natural incretin hormone released by the intestine after meals, and they are well-suited for treating type 2 diabetes

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Appetite effects: Act on brain regions controlling hunger and fullness Reduce appetite between meals Enhance feelings of satisfaction after eating Decrease food preoccupation and cravings Gastric effects: Slow stomach emptying Prolong feelings of fullness Reduce the volume of food needed to feel satisfied Metabolic effects: Improve insulin secretion (glucose-dependent) Reduce glucagon release Improve insulin sensitivity Both Saxenda and Ozempic work through these mechanisms

Small, steady habits reinforce the appetite and metabolic improvements gained from GLP-1 treatment

Clinical data are also sparse

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