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The STEP clinical trials demonstrated that semaglutide 2.4 mg weekly produced average weight loss of 15-18% over 68 weeks in non-diabetic adults with obesity or overweight status

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Reigstad CS, Salmonson CE, Rainey JF

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The STEP clinical trials demonstrated an average 14.9% reduction in body weight over 68 weeks, with one-third of participants losing over 20% of initial body weight

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