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Death from a cardiovascular event, nonfatal myocardial infarction (heart attack), or nonfatal stroke occurred during the trial in 6.5% of patients who were treated with semaglutide versus 8.0% of patients who received placebo a 20% reduction in relative risk by semaglutide

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(2015) 3:e00155

In-vivo pharmacodynamics of hydrogel-based GLP-1 RA formulations Next, we examined the ability of the hydrogel-based long-acting GLP-1 RA formulations to reduce average BG after each six-week treatment regimen