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Role of intra-islet paracrine signaling in the effects of pharmaceutical targeting of GLP-1 As current therapies focusing on increasing insulin sensitivity and/or insulin secretion fail to cure diabetes, one potentially underappreciated target for diabetes treatment is the alpha-cell
At the end of the study, mice underwent a final post-study retro-orbital bleed, and brains, separated into forebrain and hindbrain (around 3.87 mm from bregma) and inguinal and epididymal WATs, were frozen in liquid nitrogen
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