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French physiologist Jean La Barre first used the term incretine in 1932 to describe a substance which lowered glucose levels by augmenting insulin release and actions.4 5 We now know that GLP-1 and glucose-dependent insulinotropic peptide (GIP) are the two main incretin hormones
doi:10.1007/s12017-012-8184-z 136
The dosing schedule follows a similar gradual titration to minimize side effects
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