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In comparison to subcutaneous injection, for oral administration, we consider a positive signal when the odds ratio (OR) is greater than 1 and the confidence interval does not include 1

Clifford Rosen, a professor of medicine at Tufts University who has been studying the potential impact of GLP-1s on bone health

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They were initially developed to manage type 2 diabetes, but are now being explored for a broader range of uses, most popularly, in weight management but also importantly, in cardiovascular health

The Phase 3 trial showed that patients without diabetes who received the highest dose of the weekly injection lost an average of 28.3% of their body weight over 80 weeks