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In the GLP-1 RA group, 33 participants were subsequently newly diagnosed with heart failure, compared with 15 in the SGLT2i group (RR 0.44 [95% CI 0.23, 0.83] p =0.0092)

Until that data exists, Metformin remains the evidence-based choice for cardiovascular protection

Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins

A decrease in insulin secretion and activation of the counterregulatory response are the main response mechanisms for avoidance or correction of hypoglycemia

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